0306 Circadian Disrupting Light Exposure within Pediatric Hospital Rooms

Abstract Introduction Pediatric patients undergoing stem cell transplant (SCT) often experience extended hospitalizations. Inappropriate lighting during admissions is known to disrupt sleep and circadian health, which can result in worse health outcomes. This study aimed describe patterns of light across 24-hour periods two inpatient rooms children SCT. Methods Wall-mounted meters (Extech SDL400) continuously tracked noise levels at one-minute intervals patient over six months. We determined the percent time that were exposed non-optimal (< 448 lux daytime, >18 evening, >2 night); thresholds based on converting recent consensus-based melanopic equivalent daylight illuminance guidelines vertically measured thresholds. assessed frequency exceeded associated with night wakings (>150 lux). Wilcoxon rank-sum tests compared between rooms. Room A had a single northwest-facing window overlooking narrow courtyard. B an unobstructed facing north. Results On average, hospitalized pediatric SCT spent 50% their inappropriate conditions. They spikes >150 2% nights, overnight peaking 513 lux. When comparing average daytime nighttime rooms, was significantly dimmer than B, p <.001. In room, never reached recommended threshold too bright for 19% evening 17% nighttime. brighter dim 97% 59% 30% Conclusion During day, are rarely enough preserve healthy rhythm. Hospitals have opportunity improve already elevated risk morbidities transplant. Support (if any) research generously supported by grant funding from Pedals Pediatrics (PI: Zhou) institutional training (T32DK063929).